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Oncologists and other cancer doctors determine what course of treatment to pursue for every patient. The options are endless. There exists no regular treatment option for peritoneal mesothelioma patients. This is due to the cancers high mortality rate, rareness, low treatment success rate, and small number of studies to provide meaningful statistics.

While prospects for patients with mesothelioma have been bleak, doctors have been making progress. Customary treatments for cancer are surgery (removing the tumor and the tissue that surrounds it), radiation (killing the cancerous cells with radiation), and chemotherapy (poisoning the cancerous cells.) All three methods have problems. Traditional radiation therapy has not worked well with mesothelioma patients. In hopes to lessen damage to healthy tissue, researches are studying ways to aim radiation right at the tumor.

Surgery takes out the mesothelial cancerous tissue around the tumor. This surgery is extensive and it is not clear how much the patient benefits. Common chemotherapy drugs that work on other types of cancer usually do not work on mesothelioma, and different mixtures of these drugs have not been successful. Similar to radiation, focus in research is focusing on treating the physical location of the tumor with emphasis on the pleural cavity.

The death rate for mesothelioma is so high that many of even the most sophisticated techniques in cancer treatment are tried out on patients. These include biologic therapy such as the agent interleukin 2 and anti-angiogenesis drugs such as thalidomide. The new drug pemetrexed (brand name Alimta) has shown good results in extending life with mesotheliomas..

Before acting, oncologists review the stage of mesothelioma, position of the tumor, and age and health status of the patient. Two therapies that are extremely cutting-edge in fighting cancer are called photodynamic and gene therapy. Clinical trials using these techniques are being offered to some of those who have mesothelioma.

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